Cargando…
Roles for the DNA-PK complex and 53BP1 in protecting ends from resection during DNA double-strand break repair
p53-binding protein 1 (53BP1) exerts distinct impacts in different situations involving DNA double-strand break (DSB) rejoining. Here we focus on how 53BP1 impacts upon the repair of ionising radiation-induced DSBs (IR-DSBs) and how it interfaces with Ku, the DNA end-binding component of canonical n...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482155/ https://www.ncbi.nlm.nih.gov/pubmed/32779701 http://dx.doi.org/10.1093/jrr/rraa053 |