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Of mitogens and morphogens: modelling Sonic Hedgehog mechanisms in vertebrate development
Sonic Hedgehog (Shh) Is a critical protein in vertebrate development, orchestrating patterning and growth in many developing systems. First described as a classic morphogen that patterns tissues through a spatial concentration gradient, subsequent studies have revealed a more complex mechanism, in w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482217/ https://www.ncbi.nlm.nih.gov/pubmed/32829689 http://dx.doi.org/10.1098/rstb.2019.0660 |