Hydration-Induced Structural Changes in the Solid State of Protein: A SAXS/WAXS Study on Lysozyme

[Image: see text] The stability of biologically produced pharmaceuticals is the limiting factor to various applications, which can be improved by formulation in solid-state forms, mostly via lyophilization. Knowledge about the protein structure at the molecular level in the solid state and its trans...

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Detalles Bibliográficos
Autores principales: Phan-Xuan, Tuan, Bogdanova, Ekaterina, Millqvist Fureby, Anna, Fransson, Jonas, Terry, Ann E., Kocherbitov, Vitaly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482395/
https://www.ncbi.nlm.nih.gov/pubmed/32787275
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482395/
https://www.ncbi.nlm.nih.gov/pubmed/32787275
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00351

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