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Hydration-Induced Structural Changes in the Solid State of Protein: A SAXS/WAXS Study on Lysozyme
[Image: see text] The stability of biologically produced pharmaceuticals is the limiting factor to various applications, which can be improved by formulation in solid-state forms, mostly via lyophilization. Knowledge about the protein structure at the molecular level in the solid state and its trans...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482395/ https://www.ncbi.nlm.nih.gov/pubmed/32787275 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00351 |