Cargando…

Novel Vaccine That Blunts Fentanyl Effects and Sequesters Ultrapotent Fentanyl Analogues

[Image: see text] Active immunization is an emerging potential modality to combat fatal overdose amid the opioid epidemic. In this study, we described the design, synthesis, formulation, and animal testing of an efficacious vaccine against fentanyl. The vaccine formulation is composed of a novel fen...

Descripción completa

Detalles Bibliográficos
Autores principales: Barrientos, Rodell C., Bow, Eric W., Whalen, Connor, Torres, Oscar B., Sulima, Agnieszka, Beck, Zoltan, Jacobson, Arthur E., Rice, Kenner C., Matyas, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482402/
https://www.ncbi.nlm.nih.gov/pubmed/32787282
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00497