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Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

Misfolded proteins in the endoplasmic reticulum (ER) are degraded by ER-associated degradation (ERAD). Although ERAD components involved in degradation of luminal substrates are well characterized, much less is known about quality control of membrane proteins. Here, we analyzed the degradation pathw...

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Detalles Bibliográficos
Autores principales: van de Weijer, Michael L., Krshnan, Logesvaran, Liberatori, Sabrina, Guerrero, Elena Navarro, Robson-Tull, Jacob, Hahn, Lilli, Lebbink, Robert Jan, Wiertz, Emmanuel J.H.J., Fischer, Roman, Ebner, Daniel, Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482433/
https://www.ncbi.nlm.nih.gov/pubmed/32738194
http://dx.doi.org/10.1016/j.molcel.2020.07.009