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Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex
Misfolded proteins in the endoplasmic reticulum (ER) are degraded by ER-associated degradation (ERAD). Although ERAD components involved in degradation of luminal substrates are well characterized, much less is known about quality control of membrane proteins. Here, we analyzed the degradation pathw...
Autores principales: | van de Weijer, Michael L., Krshnan, Logesvaran, Liberatori, Sabrina, Guerrero, Elena Navarro, Robson-Tull, Jacob, Hahn, Lilli, Lebbink, Robert Jan, Wiertz, Emmanuel J.H.J., Fischer, Roman, Ebner, Daniel, Carvalho, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482433/ https://www.ncbi.nlm.nih.gov/pubmed/32738194 http://dx.doi.org/10.1016/j.molcel.2020.07.009 |
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