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Optopharmacology reveals a differential contribution of native GABA(A) receptors to dendritic and somatic inhibition using azogabazine

γ-aminobutyric acid type-A receptors (GABA(A)Rs) are inhibitory ligand-gated ion channels in the brain that are crucial for controlling neuronal excitation. To explore their physiological roles in cellular and neural network activity, it is important to understand why specific GABA(A)R isoforms are...

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Detalles Bibliográficos
Autores principales: Mortensen, Martin, Huckvale, Rosemary, Pandurangan, Arun P., Baker, James R., Smart, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482436/
https://www.ncbi.nlm.nih.gov/pubmed/32445639
http://dx.doi.org/10.1016/j.neuropharm.2020.108135