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Mathematical modelling of breast cancer cells in response to endocrine therapy and Cdk4/6 inhibition

Oestrogen receptor (ER)-positive breast cancer is responsive to a number of targeted therapies used clinically. Unfortunately, the continuous application of any targeted therapy often results in resistance to the therapy. Our ultimate goal is to use mathematical modelling to optimize alternating the...

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Detalles Bibliográficos
Autores principales: He, Wei, Demas, Diane M., Conde, Isabel P., Shajahan-Haq, Ayesha N., Baumann, William T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482571/
https://www.ncbi.nlm.nih.gov/pubmed/32842890
http://dx.doi.org/10.1098/rsif.2020.0339