Cargando…

BBIQ, a pure TLR7 agonist, is an effective influenza vaccine adjuvant

Better adjuvants are needed for vaccines against seasonal influenza. TLR7 agonists are potent activators of innate immune responses and thereby may be promising adjuvants. Among the imidazoquinoline compounds, 1-benzyl-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (BBIQ) was reported to be a highly acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaushik, Deepender, Dhingra, Simran, Patil, Madhuri T., Piplani, Sakshi, Khanna, Varun, Honda-Okubo, Yoshikazu, Li, Lei, Fung, Johnson, Sakala, Isaac G., Salunke, Deepak B., Petrovsky, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482670/
https://www.ncbi.nlm.nih.gov/pubmed/32298200
http://dx.doi.org/10.1080/21645515.2019.1710409