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Oral delivery of anti-TNF antibody shielded by natural polyphenol-mediated supramolecular assembly for inflammatory bowel disease therapy

Rationale: Anti-tumor necrosis factor (TNF) therapy is a very effective way to treat inflammatory bowel disease. However, systemic exposure to anti-TNF-α antibodies through current clinical systemic administration can cause serious adverse effects in many patients. Here, we report a facile prepared...

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Detalles Bibliográficos
Autores principales: Wang, Xinyu, Yan, Junjie, Wang, Lizhen, Pan, Donghui, Xu, Yuping, Wang, Fang, Sheng, Jie, Li, Xinxin, Yang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482796/
https://www.ncbi.nlm.nih.gov/pubmed/32929381
http://dx.doi.org/10.7150/thno.47601