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Recognition of G-quadruplex topology through hybrid binding with implications in cancer theranostics

The selective recognition and imaging of oncogene specific G-quadruplex (GQ) structures holds great promise in the development of diagnostic therapy (theranostics) for cancer and has been challenging due to their structural dynamics and diversity. We report selective recognition of GQ by a small mol...

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Detalles Bibliográficos
Autores principales: Suseela, Yelisetty Venkata, Satha, Pardhasaradhi, Murugan, N. Arul, Govindaraju, Thimmaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482797/
https://www.ncbi.nlm.nih.gov/pubmed/32929356
http://dx.doi.org/10.7150/thno.48675