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Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8(+) T-cell memory in wild-type and humanized mice

Conventional immunosuppressants cause side effects and do not prevent the recurrence of autoimmune diseases. Moreover, they may not inhibit autoimmunity mediated by pathogenic memory T-cells. Dihydroartemisinin (DHA) has been shown to regulate autoimmunity. However, it remains unknown whether DHA im...

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Detalles Bibliográficos
Autores principales: Chen, Yuchao, Yan, Yuhong, Liu, Huazhen, Qiu, Feifei, Liang, Chun-Ling, Zhang, Qunfang, Huang, Run-Yue, Han, Ling, Lu, Chuanjian, Dai, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482806/
https://www.ncbi.nlm.nih.gov/pubmed/32929360
http://dx.doi.org/10.7150/thno.45211