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Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir(-/-) murine psoriasis

Rationale: V-domain immunoglobulin suppressor of T cell activation (VISTA) is a novel inhibitory immune checkpoint molecule. Vsir(-/-) mice have exacerbated psoriasis-like skin inflammation. The immune cell subsets involved in inflammation in Vsir(-/-) psoriatic mice are largely unknown. We have use...

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Detalles Bibliográficos
Autores principales: Qie, Chenxin, Jiang, Jingwei, Liu, Wanmei, Hu, Xinlei, Chen, Wenting, Xie, Xiaoxue, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482809/
https://www.ncbi.nlm.nih.gov/pubmed/32929361
http://dx.doi.org/10.7150/thno.45614