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Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa

Recent advances in viral vector engineering, as well as an increased understanding of the cellular and molecular mechanism of retinal diseases, have led to the development of novel gene therapy approaches. Furthermore, ease of accessibility and ocular immune privilege makes the retina an ideal targe...

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Detalles Bibliográficos
Autores principales: Li, Sujun, Datta, Shyamtanu, Brabbit, Emily, Love, Zoe, Woytowicz, Victoria, Flattery, Kyle, Capri, Jessica, Yao, Katie, Wu, Siqi, Imboden, Michael, Upadhyay, Arun, Arumugham, Rasappa, Thoreson, Wallace B., DeAngelis, Margaret M., Haider, Neena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483267/
https://www.ncbi.nlm.nih.gov/pubmed/32123325
http://dx.doi.org/10.1038/s41434-020-0134-z