Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis

Multiple myeloma (MM) cell lines are routinely used to model the disease. However, a long-standing question is how well these cell lines truly represent tumor cells in patients. Here, we employ a recently described method of transcriptional correlation profiling to compare similarity of 66 MM cell l...

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Detalles Bibliográficos
Autores principales: Sarin, Vishesh, Yu, Katharine, Ferguson, Ian D., Gugliemini, Olivia, Nix, Matthew A., Hann, Byron, Sirota, Marina, Wiita, Arun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483300/
https://www.ncbi.nlm.nih.gov/pubmed/32123307
http://dx.doi.org/10.1038/s41375-020-0785-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483300/
https://www.ncbi.nlm.nih.gov/pubmed/32123307
http://dx.doi.org/10.1038/s41375-020-0785-1

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