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Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis
Multiple myeloma (MM) cell lines are routinely used to model the disease. However, a long-standing question is how well these cell lines truly represent tumor cells in patients. Here, we employ a recently described method of transcriptional correlation profiling to compare similarity of 66 MM cell l...
Autores principales: | Sarin, Vishesh, Yu, Katharine, Ferguson, Ian D., Gugliemini, Olivia, Nix, Matthew A., Hann, Byron, Sirota, Marina, Wiita, Arun P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483300/ https://www.ncbi.nlm.nih.gov/pubmed/32123307 http://dx.doi.org/10.1038/s41375-020-0785-1 |
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