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Microglia phagocytose myelin sheaths to modify developmental myelination
During development, oligodendrocytes contact and wrap neuronal axons with myelin. Similar to neurons and synapses, excess myelin sheaths are produced and selectively eliminated, but how elimination occurs is unknown. Microglia, the resident immune cells of the CNS, engulf surplus neurons and synapse...
Autores principales: | Hughes, Alexandria N., Appel, Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483351/ https://www.ncbi.nlm.nih.gov/pubmed/32632287 http://dx.doi.org/10.1038/s41593-020-0654-2 |
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