Aggrecan and COMP Improve Periosteal Chondrogenesis by Delaying Chondrocyte Hypertrophic Maturation

The generation of cartilage from progenitor cells for the purpose of cartilage repair is often hampered by hypertrophic differentiation of the engineered cartilaginous tissue caused by endochondral ossification. Since a healthy cartilage matrix contains high amounts of Aggrecan and COMP, we hypothes...

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Detalles Bibliográficos
Autores principales: Caron, Marjolein M. J., Janssen, Maarten P. F., Peeters, Laura, Haudenschild, Dominik R., Cremers, Andy, Surtel, Don A. M., van Rhijn, Lodewijk W., Emans, Pieter J., Welting, Tim J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483497/
https://www.ncbi.nlm.nih.gov/pubmed/32984292
http://dx.doi.org/10.3389/fbioe.2020.01036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483497/
https://www.ncbi.nlm.nih.gov/pubmed/32984292
http://dx.doi.org/10.3389/fbioe.2020.01036

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