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Progressive long‐term spatial memory loss following repeat concussive and subconcussive brain injury in mice, associated with dorsal hippocampal neuron loss, microglial phenotype shift, and vascular abnormalities

There is considerable concern about the long‐term deleterious effects of repeat head trauma on cognition, but little is known about underlying mechanisms and pathology. To examine this, we delivered four air blasts to the left side of the mouse cranium, a week apart, with an intensity that causes de...

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Detalles Bibliográficos
Autores principales: Honig, Marcia G., Dorian, Conor C., Worthen, John D., Micetich, Anthony C., Mulder, Isabelle A., Sanchez, Katelyn B., Pierce, William F., Del Mar, Nobel A., Reiner, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483557/
https://www.ncbi.nlm.nih.gov/pubmed/32090401
http://dx.doi.org/10.1111/ejn.14711