The Paradox of HIV Blood–Brain Barrier Penetrance and Antiretroviral Drug Delivery Deficiencies

HIV attacks the body’s immune cells, frequently compromises the integrity of the blood–brain barrier (BBB), and infects the CNS in the early stages of infection. Dysfunction of the BBB further potentiates viral replication within the CNS, which can lead to HIV-associated neuropathology. Antiretrovir...

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Detalles Bibliográficos
Autores principales: Osborne, Olivia, Peyravian, Nadia, Nair, Madhavan, Daunert, Sylvia, Toborek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483662/
https://www.ncbi.nlm.nih.gov/pubmed/32682564
http://dx.doi.org/10.1016/j.tins.2020.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483662/
https://www.ncbi.nlm.nih.gov/pubmed/32682564
http://dx.doi.org/10.1016/j.tins.2020.06.007

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