The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development

Complement-mediated synapse elimination has emerged as an important process in both brain development and neurological diseases, but whether neurons express complement inhibitors that protect synapses against complement-mediated synapse elimination remains unknown. Here, we show that the sushi domai...

Descripción completa

Detalles Bibliográficos
Autores principales: Cong, Qifei, Soteros, Breeanne M., Wollet, Mackenna, Kim, Jun Hee, Sia, Gek-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483802/
https://www.ncbi.nlm.nih.gov/pubmed/32661396
http://dx.doi.org/10.1038/s41593-020-0672-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483802/
https://www.ncbi.nlm.nih.gov/pubmed/32661396
http://dx.doi.org/10.1038/s41593-020-0672-0

Ejemplares similares