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The endogenous neuronal complement inhibitor SRPX2 protects against complement-mediated synapse elimination during development
Complement-mediated synapse elimination has emerged as an important process in both brain development and neurological diseases, but whether neurons express complement inhibitors that protect synapses against complement-mediated synapse elimination remains unknown. Here, we show that the sushi domai...
Autores principales: | Cong, Qifei, Soteros, Breeanne M., Wollet, Mackenna, Kim, Jun Hee, Sia, Gek-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483802/ https://www.ncbi.nlm.nih.gov/pubmed/32661396 http://dx.doi.org/10.1038/s41593-020-0672-0 |
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