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Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction

INTRODUCTION: Macrophages and neutrophils are primary leukocytes involved in the inflammatory response to myocardial infarction (MI). While interleukin (IL)-4 is an in vitro anti-inflammatory stimulus, the MI myocardium does not express a considerable amount of IL-4 but does express IL4 receptors. W...

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Detalles Bibliográficos
Autores principales: Daseke, Michael J., Tenkorang-Impraim, Mavis A.A., Ma, Yonggang, Chalise, Upendra, Konfrst, Shelby R., Garrett, Michael R., DeLeon-Pennell, Kristine Y., Lindsey, Merry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483959/
https://www.ncbi.nlm.nih.gov/pubmed/32574573
http://dx.doi.org/10.1016/j.yjmcc.2020.06.006