Development and Evaluation of a High Throughput Inhalation Model for Organic Chemicals

Currently it is difficult to prospectively estimate human toxicokinetics (particularly for novel chemicals) in a high-throughput manner. The R software package httk has been developed, in part, to address this deficiency, and the aim of this investigation was to develop a generalized inhalation mode...

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Detalles Bibliográficos
Autores principales: Linakis, Matthew W., Sayre, Risa R., Pearce, Robert G., Sfeir, Mark A., Sipes, Nisha S., Pangburn, Heather A., Gearhart, Jeffery M., Wambaugh, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483974/
https://www.ncbi.nlm.nih.gov/pubmed/32546826
http://dx.doi.org/10.1038/s41370-020-0238-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483974/
https://www.ncbi.nlm.nih.gov/pubmed/32546826
http://dx.doi.org/10.1038/s41370-020-0238-y

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