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Development and Evaluation of a High Throughput Inhalation Model for Organic Chemicals
Currently it is difficult to prospectively estimate human toxicokinetics (particularly for novel chemicals) in a high-throughput manner. The R software package httk has been developed, in part, to address this deficiency, and the aim of this investigation was to develop a generalized inhalation mode...
Autores principales: | Linakis, Matthew W., Sayre, Risa R., Pearce, Robert G., Sfeir, Mark A., Sipes, Nisha S., Pangburn, Heather A., Gearhart, Jeffery M., Wambaugh, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483974/ https://www.ncbi.nlm.nih.gov/pubmed/32546826 http://dx.doi.org/10.1038/s41370-020-0238-y |
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