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Exosome mimicry by an HAVCR1/NPC1 pathway of endosomal fusion mediates hepatitis A virus infection

Cell-to-cell communication by exosomes controls normal and pathogenic processes(1,2). Viruses can spread in exosomes and thereby avoid immune recognition(3). While biogenesis, binding, and uptake of exosomes are well-characterized(4,5), delivery of exosome cargo into the cytoplasm is poorly understo...

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Detalles Bibliográficos
Autores principales: Costafreda, Maria Isabel, Abbasi, Abdolrahim, Lu, Hsinyi, Kaplan, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483988/
https://www.ncbi.nlm.nih.gov/pubmed/32541946
http://dx.doi.org/10.1038/s41564-020-0740-y