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Genetic variability in the expression of the SARS-CoV-2 host cell entry factors across populations

The entry of SARS-CoV-2 into host cells is dependent upon angiotensin-converting enzyme 2 (ACE2), which serves as a functional attachment receptor for the viral spike glycoprotein, and the serine protease TMPRSS2 which allows fusion of the viral and host cell membranes. We devised a quantitative mea...

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Detalles Bibliográficos
Autores principales: Ortiz-Fernández, Lourdes, Sawalha, Amr H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484169/
https://www.ncbi.nlm.nih.gov/pubmed/32759995
http://dx.doi.org/10.1038/s41435-020-0107-7