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Steroid 5α-Reductase Type I Induces Cell Viability and Migration via Nuclear Factor-κB/Vascular Endothelial Growth Factor Signaling Pathway in Colorectal Cancer

Colorectal cancer (CRC) is a common malignant tumor of the digestive system. Steroid 5α-reductase type I (SRD5A1), as an important part of the steroid metabolism, converts testosterone to dihydrotestosterone and regulates sex hormone levels, which accommodates tumor occurrence or development. Howeve...

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Detalles Bibliográficos
Autores principales: Wei, Rongfang, Zhong, Sixia, Qiao, Li, Guo, Mengjie, Shao, Miaomiao, Wang, Suyu, Jiang, Bin, Yang, Ye, Gu, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484213/
https://www.ncbi.nlm.nih.gov/pubmed/32983992
http://dx.doi.org/10.3389/fonc.2020.01501