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Lymph protects metastasizing melanoma cells from ferroptosis

Cancer cells, including melanoma, often metastasize regionally through lymphatics before metastasizing systemically through the blood(1–4); however, the reason for this is unclear. Here we show that melanoma cells in lymph experience less oxidative stress and form more metastases than melanoma cells...

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Detalles Bibliográficos
Autores principales: Ubellacker, Jessalyn M., Tasdogan, Alpaslan, Ramesh, Vijayashree, Shen, Bo, Mitchell, Evann C., Martin-Sandoval, Misty S., Gu, Zhimin, McCormick, Michael L., Durham, Alison B., Spitz, Douglas R., Zhao, Zhiyu, Mathews, Thomas P., Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484468/
https://www.ncbi.nlm.nih.gov/pubmed/32814895
http://dx.doi.org/10.1038/s41586-020-2623-z