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Lymph protects metastasizing melanoma cells from ferroptosis
Cancer cells, including melanoma, often metastasize regionally through lymphatics before metastasizing systemically through the blood(1–4); however, the reason for this is unclear. Here we show that melanoma cells in lymph experience less oxidative stress and form more metastases than melanoma cells...
Autores principales: | Ubellacker, Jessalyn M., Tasdogan, Alpaslan, Ramesh, Vijayashree, Shen, Bo, Mitchell, Evann C., Martin-Sandoval, Misty S., Gu, Zhimin, McCormick, Michael L., Durham, Alison B., Spitz, Douglas R., Zhao, Zhiyu, Mathews, Thomas P., Morrison, Sean J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484468/ https://www.ncbi.nlm.nih.gov/pubmed/32814895 http://dx.doi.org/10.1038/s41586-020-2623-z |
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