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Defined Mathematical Relationships Among Cancer Cells Suggest Modular Growth in Tumor Progression and Highlight Developmental Features Consistent With a Para-Embryonic Nature of Cancer

Several similarities between the embryo development and the cancer process suggest the para-embryonic nature of tumors. Starting from an initial cancer stem cell (i-CSC) as a para-embryonic stem cell (p-ESC), a hierarchic sequence of CSCs (CSC(1)s, CSC(2)s, CSC(3)s) and non-CSCs [cancer progenitor c...

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Detalles Bibliográficos
Autor principal: Manzo, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484490/
https://www.ncbi.nlm.nih.gov/pubmed/32984319
http://dx.doi.org/10.3389/fcell.2020.00804