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Amyloid-ß peptides inhibit the expression of AQP4 and glutamate transporter EAAC1 in insulin-treated C6 glioma cells

Astrocytic aquaporin 4 (AQP4) facilitates glutamate clearance via regulation of the glutamate transporter function, involved in the modulation of brain plasticity and cognitive function to prevent neurodegenerative disorders such as Alzheimer’s disease (AD). In in vitro studies, the C6 rat glioma ce...

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Detalles Bibliográficos
Autores principales: Park, Se-Ho, Lee, Jae-Yeul, Jhee, Kwang-Hwan, Yang, Seun-Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484518/
https://www.ncbi.nlm.nih.gov/pubmed/32953460
http://dx.doi.org/10.1016/j.toxrep.2020.08.032