Nicotine increases alcohol self‐administration in male rats via a μ‐opioid mechanism within the mesolimbic pathway

BACKGROUND AND PURPOSE: Alcohol and nicotine use disorders are commonly comorbid. Both alcohol and nicotine can activate opioid systems in reward‐related brain regions, leading to adaptive changes in opioid signalling upon chronic exposure. The potential role of these adaptations for comorbidity is...

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Detalles Bibliográficos
Autores principales: Domi, Esi, Xu, Li, Pätz, Marvin, Nordeman, Anton, Augier, Gaëlle, Holm, Lovisa, Toivainen, Sanne, Augier, Eric, Hansson, Anita C., Heilig, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484560/
https://www.ncbi.nlm.nih.gov/pubmed/32697329
http://dx.doi.org/10.1111/bph.15210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484560/
https://www.ncbi.nlm.nih.gov/pubmed/32697329
http://dx.doi.org/10.1111/bph.15210

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