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Conjugation of TLR7 Agonist Combined with Demethylation Treatment Improves Whole-Cell Tumor Vaccine Potency in Acute Myeloid Leukemia

Background: Acute myeloid leukemia (AML) is a malignant hematological disease with high refractory rate. Immune escape of AML cells is one of the underlying mechanisms mediating the relapse of the cancers. Various immunotherapies based on the 'patients' immune response to tumor cells have...

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Detalles Bibliográficos
Autores principales: Zhong, Guocheng, Jin, Guangyi, Zeng, Wei, Yu, Changhua, Li, Yan, Zhou, Ji, Zhang, Li, Yu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484644/
https://www.ncbi.nlm.nih.gov/pubmed/32922200
http://dx.doi.org/10.7150/ijms.49983