Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes

Clusterin, a glycoprotein encoded by the CLU gene, is expressed in many tissues, including the kidney, and clusterin expression is upregulated in the glomeruli of patients with various forms of kidney disease. Here, we investigated the role of clusterin in diabetic nephropathy (DN). In this study, w...

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Detalles Bibliográficos
Autores principales: He, Junling, Dijkstra, Kyra L., Bakker, Kim, Bus, Pascal, Bruijn, Jan A., Scharpfenecker, Marion, Baelde, Hans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484791/
https://www.ncbi.nlm.nih.gov/pubmed/32913257
http://dx.doi.org/10.1038/s41598-020-71629-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484791/
https://www.ncbi.nlm.nih.gov/pubmed/32913257
http://dx.doi.org/10.1038/s41598-020-71629-z

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