Cargando…
Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes
Clusterin, a glycoprotein encoded by the CLU gene, is expressed in many tissues, including the kidney, and clusterin expression is upregulated in the glomeruli of patients with various forms of kidney disease. Here, we investigated the role of clusterin in diabetic nephropathy (DN). In this study, w...
Autores principales: | He, Junling, Dijkstra, Kyra L., Bakker, Kim, Bus, Pascal, Bruijn, Jan A., Scharpfenecker, Marion, Baelde, Hans J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484791/ https://www.ncbi.nlm.nih.gov/pubmed/32913257 http://dx.doi.org/10.1038/s41598-020-71629-z |
Ejemplares similares
-
Endothelial Endothelin Receptor A Expression Is Associated With Podocyte Injury and Oxidative Stress in Patients With Focal Segmental Glomerulosclerosis
por: van de Lest, Nina A., et al.
Publicado: (2021) -
Endoglin Promotes Myofibroblast Differentiation and Extracellular Matrix Production in Diabetic Nephropathy
por: Gerrits, Tessa, et al.
Publicado: (2020) -
The VEGF-A inhibitor sFLT-1 improves renal function by reducing endothelial activation and inflammation in a mouse model of type 1 diabetes
por: Bus, Pascal, et al.
Publicado: (2017) -
Endoglin Is an Important Mediator in the Final Common Pathway of Chronic Kidney Disease to End-Stage Renal Disease
por: Gerrits, Tessa, et al.
Publicado: (2022) -
Podocyte Pathology and Nephropathy – Sphingolipids in Glomerular Diseases
por: Merscher, Sandra, et al.
Publicado: (2014)