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Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer

Colon tumors grow in an adipose tissue-enriched microenvironment. Locally advanced colon cancers often invade into surrounding adipose tissue with a direct contact with adipocytes. We have previously shown that adipocytes promote tumor growth by modulating cellular metabolism. Here we demonstrate th...

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Detalles Bibliográficos
Autores principales: Xiong, Xiaopeng, Wen, Yang-An, Fairchild, Rachelle, Zaytseva, Yekaterina Y., Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484798/
https://www.ncbi.nlm.nih.gov/pubmed/32913185
http://dx.doi.org/10.1038/s41419-020-02936-6