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Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer
Colon tumors grow in an adipose tissue-enriched microenvironment. Locally advanced colon cancers often invade into surrounding adipose tissue with a direct contact with adipocytes. We have previously shown that adipocytes promote tumor growth by modulating cellular metabolism. Here we demonstrate th...
Autores principales: | Xiong, Xiaopeng, Wen, Yang-An, Fairchild, Rachelle, Zaytseva, Yekaterina Y., Weiss, Heidi L., Evers, B. Mark, Gao, Tianyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484798/ https://www.ncbi.nlm.nih.gov/pubmed/32913185 http://dx.doi.org/10.1038/s41419-020-02936-6 |
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