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Topical Melatonin Improves Gastric Microcirculatory Oxygenation During Hemorrhagic Shock in Dogs but Does Not Alter Barrier Integrity of Caco-2 Monolayers

Systemic administration of melatonin exerts tissue protective effects in the context of hemorrhagic shock. Intravenous application of melatonin prior to hemorrhage improves gastric microcirculatory perfusion and maintains intestinal barrier function in dogs. The aim of the present study was to analy...

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Detalles Bibliográficos
Autores principales: Truse, Richard, Nolten, Inga, Schulz, Jan, Herminghaus, Anna, Holtmanns, Tobias, Gördes, Lukas, Raupach, Annika, Bauer, Inge, Picker, Olaf, Vollmer, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484810/
https://www.ncbi.nlm.nih.gov/pubmed/32984383
http://dx.doi.org/10.3389/fmed.2020.00510