Supplementation of l‐arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy

Myeloid‐derived suppressor cells (MDSCs) play a crucial role in immunosuppression in tumor‐bearing hosts. MDSCs express arginase‐I and indoleamine 2,3‐dioxygenase; they suppress T‐cell function by reducing the levels of l‐arginine and l‐tryptophan, respectively. We examined the anticancer effects of...

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Detalles Bibliográficos
Autores principales: Satoh, Yusuke, Kotani, Hitoshi, Iida, Yuichi, Taniura, Takahito, Notsu, Yoshitomo, Harada, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484823/
https://www.ncbi.nlm.nih.gov/pubmed/32426941
http://dx.doi.org/10.1111/cas.14490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484823/
https://www.ncbi.nlm.nih.gov/pubmed/32426941
http://dx.doi.org/10.1111/cas.14490

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