Squalene epoxidase‐induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling

Nasopharyngeal carcinoma (NPC) is a common malignant tumor and a major cause of mortality and morbidity in southern China. However, the mechanism is still elusive. Here, we focused on studying the role of squalene epoxidase (SQLE), a key enzyme of cholesterol biosynthesis, in the progression of NPC....

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Detalles Bibliográficos
Autores principales: Li, Liming, Zhang, Qingfeng, Wang, Xin, Li, Yan, Xie, Huifen, Chen, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484843/
https://www.ncbi.nlm.nih.gov/pubmed/32314495
http://dx.doi.org/10.1111/cas.14426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484843/
https://www.ncbi.nlm.nih.gov/pubmed/32314495
http://dx.doi.org/10.1111/cas.14426

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