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Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer

Cancer cells utilize the forces of natural selection to evolve evolvability allowing a constant supply of heritable variation that permits a cancer species to evolutionary track changing hazards and opportunities. Over time, the dynamic tumor ecosystem is exposed to extreme, catastrophic changes in...

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Detalles Bibliográficos
Autores principales: Pienta, Kenneth J., Hammarlund, Emma U., Axelrod, Robert, Brown, Joel S., Amend, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484876/
https://www.ncbi.nlm.nih.gov/pubmed/32952609
http://dx.doi.org/10.1111/eva.12929