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Poly‐aneuploid cancer cells promote evolvability, generating lethal cancer
Cancer cells utilize the forces of natural selection to evolve evolvability allowing a constant supply of heritable variation that permits a cancer species to evolutionary track changing hazards and opportunities. Over time, the dynamic tumor ecosystem is exposed to extreme, catastrophic changes in...
Autores principales: | Pienta, Kenneth J., Hammarlund, Emma U., Axelrod, Robert, Brown, Joel S., Amend, Sarah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484876/ https://www.ncbi.nlm.nih.gov/pubmed/32952609 http://dx.doi.org/10.1111/eva.12929 |
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