Cargando…

Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions

Methotrexate (MTX) is a chemotherapeutic agent and an immunosuppressant used to treat cancer and autoimmune diseases. However, its use is limited by its multi-organ toxicity, including nephrotoxicity, which is related to MTX-driven oxidative stress. Silencing oxidative stressors is therefore an impo...

Descripción completa

Detalles Bibliográficos
Autores principales: Abouelela, Mohamed E., Orabi, Mohamed A.A., Abdelhamid, Reda A., Abdelkader, Mohamed S., Madkor, Hafez R., Darwish, Faten M.M., Hatano, Tsutomu, Elsadek, Bakheet E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484958/
https://www.ncbi.nlm.nih.gov/pubmed/32953564
http://dx.doi.org/10.1016/j.jtcme.2019.08.006