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In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)(6)-NH(2) and Lau-(Lys-βNspe)(6)-NH(2) Against PMA-Induced Acute Inflammation

Host Defense Peptides (HDPs) are key components of innate immunity that exert antimicrobial, antibiofilm, and immunomodulatory activities in all higher organisms. Synthetic peptidomimetic analogs were designed to retain the desirable pharmacological properties of HDPs while having improved stability...

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Detalles Bibliográficos
Autores principales: Wu, Bing C., Skovbakke, Sarah L., Masoudi, Hamid, Hancock, Robert E. W., Franzyk, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485003/
https://www.ncbi.nlm.nih.gov/pubmed/32983167
http://dx.doi.org/10.3389/fimmu.2020.02102