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In vivo Anti-inflammatory Activity of Lipidated Peptidomimetics Pam-(Lys-βNspe)(6)-NH(2) and Lau-(Lys-βNspe)(6)-NH(2) Against PMA-Induced Acute Inflammation
Host Defense Peptides (HDPs) are key components of innate immunity that exert antimicrobial, antibiofilm, and immunomodulatory activities in all higher organisms. Synthetic peptidomimetic analogs were designed to retain the desirable pharmacological properties of HDPs while having improved stability...
Autores principales: | Wu, Bing C., Skovbakke, Sarah L., Masoudi, Hamid, Hancock, Robert E. W., Franzyk, Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485003/ https://www.ncbi.nlm.nih.gov/pubmed/32983167 http://dx.doi.org/10.3389/fimmu.2020.02102 |
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