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Normal Ethanol Sensitivity and Rapid Tolerance Require the G Protein Receptor Kinase 2 in Ellipsoid Body Neurons in Drosophila

BACKGROUND: G protein signaling pathways are key neuromodulatory mechanisms for behaviors and neurological functions that affect the impact of ethanol (EtOH) on locomotion, arousal, and synaptic plasticity. Here, we report a novel role for the Drosophila G protein–coupled receptor kinase 2 (GPRK2) a...

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Detalles Bibliográficos
Autores principales: Kang, Yuan Yuan, Wachi, Yusuke, Engdorf, Elizabeth, Fumagalli, Emiliano, Wang, Youyou, Myers, Jennifer, Massey, Shebna, Greiss, Antony, Xu, Shiyu, Roman, Gregg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485117/
https://www.ncbi.nlm.nih.gov/pubmed/32573992
http://dx.doi.org/10.1111/acer.14396