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Development of HiBiT-Tagged Recombinant Infectious Bronchitis Coronavirus for Efficient in vitro and in vivo Viral Quantification

Coronaviruses (CoVs) are enveloped (+) ssRNA viruses of veterinary and medical importance. Because recombinant CoVs with reporter proteins fused with viral proteins are usually non-viable or unstable, a small and quantifiable epitope tag would be beneficial to CoV research. In this study, we integra...

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Detalles Bibliográficos
Autores principales: Liang, Xiao Ying, Zhu, Qing Chun, Liang, Jia Qi, Liu, Si Ying, Liu, Ding Xiang, Fung, To Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485224/
https://www.ncbi.nlm.nih.gov/pubmed/32983065
http://dx.doi.org/10.3389/fmicb.2020.02100