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Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells

Muscle dystrophin–glycoprotein complex (DGC) links the intracellular cytoskeleton to the extracellular matrix. In neurons, dystroglycan and dystrophin, two major components of the DGC, localize in a subset of GABAergic synapses, where their function is unclear. Here we used mouse models to analyze t...

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Detalles Bibliográficos
Autores principales: Briatore, Federica, Pregno, Giulia, Di Angelantonio, Silvia, Frola, Elena, De Stefano, Maria Egle, Vaillend, Cyrille, Sassoè-Pognetto, Marco, Patrizi, Annarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485281/
https://www.ncbi.nlm.nih.gov/pubmed/32982691
http://dx.doi.org/10.3389/fnmol.2020.00164